Working in comics since 2005, Opeña got his start with Metal Hurlant for Humanoids Publishing and has since worked on projects with Dark Horse Comics, Image Comics, and Marvel such as “Fear Agent” and “Uncanny X-Force”, as well as “The Avengers” and “Infinity” with Jonathan Hickman.

Opeña also has his creator-owned book, “Seven to Eternity”, with frequent collaborator Rick Remender.